Related Experiment Video
Updated: Jun 23, 2026
A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
Published on: March 21, 2025
[Frontal mass simulating lipoma as a clinical presentation of prostatic adenocarcinoma]
Pablo Luis Guzman Martinez-Valls1, Almudena Rodríguez Tardido, Beatriz Honrubia Vilchez
1Servicio de Urología, Hospital General Universitario Morales Meseguer, Murcia, España. pabloguzman@terra.es
Objective:
To report one case of metastatic prostatic carcinoma with a gaudy presentation as a lump which resulted to be a cutaneous metastasis.
Methods:
We describe the debut in a patient, who thanks to the pathologic analysis of a lesion mimicking a lipoma, which was reported as adenocarcinoma, was worked up for prostatic adenocarcinoma and diagnosis was reached. We performed a bibliographic review using an electronic bibliographic search in PubMed (MEDLINE) using the terms "Prostatic Neoplasm" (MesH) AND "Neoplasm Metastasis" (MesH) AND "cutaneous" (free text). Most publications are case reports reviewing the probable dissemination way and localization.
Results:
Positive immunohistochemical staining for PSA confirmed the origin of the metastasis, although PSA value did not offer doubts due to its value over 1100 ng/ml. Regarding the bibliographic search we obtained more than 26 papers, and selected only 8 that were adjusted to the objectives of our work. Cutaneous metastasis of prostatic origin appear in less than 0.3% of the cases, because bone, lymph node, and visceral disease are more frequent. Cases appearing during the evolution of the disease and metastasis after laparoscopic procedures are described.
Conclusions:
Cutaneous metastases of prostatic adenocarcinoma are very rare, but even rarer is it being the debut of the disease.
