Related Experiment Video
Updated: Jun 23, 2026
Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay
Published on: September 9, 2012
Roles for vitamin K beyond coagulation
1Vitamin K Laboratory, Jean Mayer USDA Human Nutrition Research Center at Tufts University, Boston, MA 02111, USA. sarah.booth@tufts.edu
Abstract:
Recent interest in vitamin K has been motivated by evidence of physiological roles beyond that of coagulation. Vitamin K and vitamin K-dependent (VKD) proteins may be involved in regulation of calcification, energy metabolism, and inflammation. However, the evidence for many of these proposed roles in the maintenance of health is equivocal. There is also an emerging viewpoint that the biochemical function of vitamin K may extend beyond that of a cofactor for the VKD carboxylation of glutamyl residues (Glus) to carboxylated Glus in VKD proteins.
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