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Related Experiment Video

Updated: Jun 23, 2026

Hyponeophagia: A Measure of Anxiety in the Mouse

Hyponeophagia: A Measure of Anxiety in the Mouse

Published on: May 17, 2011

[First-bite syndrome].

Montserrat Borràs-Perera¹, Juan C Fortuny-Llanses, Víctor Palomar-Asenjo

¹Servicio Otorrinolaringología y Patología Cérvico Facial, Hospital Universitari Arnau de Vilanova, Universitat de Lleida, Lleida, Spain. monboper@hotmail.com

Acta Otorrinolaringologica Espanola

|April 30, 2009

Summary

First-bite syndrome causes parotid pain during chewing due to sympathetic nerve damage. This case highlights first-bite syndrome occurring after surgery for a cervical sympathetic chain schwannoma.

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Last Updated: Jun 23, 2026

Hyponeophagia: A Measure of Anxiety in the Mouse

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Published on: May 17, 2011

Sucrose Preference and Novelty-Induced Hypophagia Tests in Rats using an Automated Food Intake Monitoring System

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Published on: May 8, 2020

Area of Science:

Neurology
Otolaryngology

Background:

First-bite syndrome is characterized by parotid pain at the onset of mastication.
It results from injury to the cervical sympathetic chain or parotid gland's sympathetic plexus.

Observation:

Diagnosis is often suggested by clinical presentation in patients with prior parapharyngeal space surgery.
This report details a case of first-bite syndrome following surgical treatment for a cervical sympathetic chain schwannoma.

Findings:

The patient developed first-bite syndrome post-operatively.
The underlying cause was a schwannoma of the cervical sympathetic chain.

Implications:

This case expands the understanding of potential etiologies for first-bite syndrome.
It underscores the importance of considering nerve injury in patients presenting with these symptoms after relevant surgery.