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Published on: August 23, 2016
Papillary glioneuronal tumor-evidence of stem cell origin with biphenotypic differentiation
Aparna Govindan1, A Mahadevan2, D I Bhat3
1Department of Neuropathology, National Institute of Mental Health & Neurosciences, Bangalore, 560 029, India.
Abstract:
Papillary glioneuronal tumors are newly recognized seizure producing tumors. We report two such cases with immunohistochemical characterization of glial and neuronal components and briefly review literature. Co-localization of glial and neuronal markers was demonstrable on confocal microscopy with expression of stem cell markers (Nestin and CD133) suggesting possible origin from neuroepithelial stem cell with biphenotypic differentiation.

