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Peritonitis rates and common microorganisms in continuous ambulatory peritoneal dialysis and automated peritoneal

Sema Akman1, Sevcan A Bakkaloglu, Mesiha Ekim

  • 1Department of Pediatric Nephrology, Akdeniz University School of Medicine, Antalya, Turkey. semaakman2002@yahoo.com

Pediatrics International : Official Journal of the Japan Pediatric Society
|May 2, 2009
PubMed

Insights

Peritonitis rates were similar between continuous ambulatory peritoneal dialysis (CAPD) and automated peritoneal dialysis (APD) in Turkish children. However, automated peritoneal dialysis (APD) showed a higher risk of Gram-negative peritonitis compared to CAPD.

Area of Science:

  • Pediatric Nephrology
  • Renal Replacement Therapy
  • Infectious Disease Epidemiology

Background:

  • Chronic peritoneal dialysis is a key treatment for pediatric kidney disease.
  • Peritonitis remains a significant complication, impacting treatment efficacy and patient outcomes.
  • Understanding peritonitis rates and causative organisms is crucial for optimizing dialysis protocols.

Purpose of the Study:

  • To investigate peritonitis rates and causative organisms in Turkish children undergoing chronic peritoneal dialysis.
  • To analyze trends in peritonitis over time across different dialysis modalities.
  • To compare peritonitis risk between continuous ambulatory peritoneal dialysis (CAPD) and automated peritoneal dialysis (APD).

Main Methods:

  • A multicenter retrospective study involving twelve pediatric renal units in Turkey.
  • Data collected through the review of medical records for 212 pediatric patients.
  • Analysis of peritonitis episodes, causative organisms, and dialysis modality (CAPD, APD, or both).

Main Results:

  • The overall peritonitis rate was 1 episode per 15.5 patient-months.
  • Peritonitis rates were comparable between CAPD (1/15.6 patient-months) and APD (1/15.4 patient-months).
  • Coagulase-negative staphylococcus was the most frequent cause (20.6%); Gram-negative infections showed a significantly higher incidence in APD (P=0.03) compared to CAPD (P=0.68).

Conclusions:

  • Peritonitis incidence is similar for CAPD and APD in pediatric patients.
  • Automated peritoneal dialysis (APD) is associated with an increased risk of Gram-negative peritonitis compared to CAPD.
  • These findings highlight the need for targeted strategies to reduce Gram-negative infections in APD.
Abstract

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