Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Adapting the spanish healthcare system for disease-modifying treatments in early-stage alzheimer's disease.

The journal of prevention of Alzheimer's disease·2026
Same author

Robot-assisted insular stereoelectroencephalography in pediatric drug-resistant epilepsy: accuracy and diagnostic value.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery·2024
Same author

Multidisciplinary radio-guided surgery team: Alternative to change the current paradigm.

Revista espanola de medicina nuclear e imagen molecular·2024
Same author

Patients with deep brain electrodes undergoing other diagnostic or therapeutic interventions. What should we take into account? Letter to the editor regarding the article "Anesthetic considerations in placement of brain electrodes for anorexia surgery".

Revista espanola de anestesiologia y reanimacion·2023
Same author

Sentinel node referent nurse: Description, validation and application in clinical practice.

Revista espanola de medicina nuclear e imagen molecular·2022
Same author

Nuclear medicine training and practice in Spain.

European journal of nuclear medicine and molecular imaging·2013
Same journal

[Revista Española de Medicina Nuclear 2004-2011. Mission accomplished].

Revista espanola de medicina nuclear·2011
Same journal

[An exciting period, "the best is always to come"].

Revista espanola de medicina nuclear·2011
Same journal

[Evaluation of the sentinel lymph node combining SPECT/CT with the planar image and its importance for the surgical act].

Revista espanola de medicina nuclear·2011
Same journal

[Diagnostic imaging studies: do they create anxiety?].

Revista espanola de medicina nuclear·2011
Same journal

Frontal meningioma on 99mTc-MIBI scan for postoperative evaluation of differentiated thyroid cancer.

Revista espanola de medicina nuclear·2011
Same journal

[Advances in a two year adventure].

Revista espanola de medicina nuclear·2011
See all related articles

Related Experiment Video

Updated: Jun 23, 2026

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients
09:32

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients

Published on: December 18, 2016

[Peri-ictal SPECT in temporal lobe epilepsy: post-surgical evaluation].

X Setoain Perego1, M Carreño Delgado, J Rumià Arboix

  • 1Servicio de Medicina Nuclear, Hospital Clínic i Provincial, Barcelona, Spain. setoain@clinic.ub.es

Revista Espanola De Medicina Nuclear
|May 2, 2009
PubMed
Summary
This summary is machine-generated.

Peri-ictal SPECT effectively localizes the epileptogenic region in temporal lobe epilepsy surgery candidates. This imaging technique shows high concordance and positive predictive value, especially when MRI and EEG results are unclear.

More Related Videos

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study
11:29

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Published on: August 15, 2025

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
09:57

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy

Published on: September 20, 2024

Related Experiment Videos

Last Updated: Jun 23, 2026

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients
09:32

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients

Published on: December 18, 2016

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study
11:29

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Published on: August 15, 2025

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
09:57

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy

Published on: September 20, 2024

Area of Science:

  • Neurology
  • Medical Imaging
  • Epilepsy Surgery

Background:

  • Medically refractory complex partial seizures (CPS) often necessitate surgical intervention.
  • Temporal lobectomy is a common surgical treatment for drug-resistant epilepsy.
  • Accurate localization of the epileptogenic region (ER) is crucial for successful surgical outcomes.

Purpose of the Study:

  • To evaluate the utility of peri-ictal single-photon emission computed tomography (SPECT) in identifying the ER.
  • To compare peri-ictal SPECT with MRI and video-electroencephalography (video-EEG) for ER localization.
  • To determine the positive predictive value (PPV) of peri-ictal SPECT in patients with good surgical outcomes.

Main Methods:

  • Retrospective analysis of 37 patients with temporal lobe epilepsy undergoing surgery.
  • Pre-surgical evaluation included video-EEG, MRI, interictal SPECT, and peri-ictal SPECT (ictal or postictal).
  • Comparison of imaging and EEG findings with the surgically confirmed ER and post-surgical seizure control (minimum 3-year follow-up).

Main Results:

  • Peri-ictal SPECT showed 86% concordance with the ER, comparable to video-EEG (86%) and superior to interictal SPECT (54%).
  • MRI demonstrated 84% concordance with the ER.
  • In patients with good surgical outcomes (n=29), peri-ictal SPECT had a PPV of 90%, similar to MRI (90%) and video-EEG (95%).

Conclusions:

  • Peri-ictal SPECT is a valuable tool for localizing the ER in temporal lobe epilepsy.
  • Its diagnostic performance is comparable to video-EEG and MRI.
  • Peri-ictal SPECT is particularly recommended when MRI and EEG findings are discordant, aiding pre-surgical planning.