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Electrocardiographic pattern in arrhythmogenic right ventricular cardiomyopathy
Alexandros Klavdios Steriotis1, Barbara Bauce, Luciano Daliento
1Department of Cardiac, Thoracic, and Vascular Sciences, University of Padua Medical School, Padua, Italy.
Electrocardiograms (ECGs) and signal-averaged ECGs (SAECGs) frequently show abnormalities in arrhythmogenic right ventricular cardiomyopathy (ARVC) patients, correlating with disease severity. These noninvasive tests are crucial for ARVC diagnosis and assessment.
Area of Science:
- Cardiology
- Medical Diagnostics
Background:
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) involves progressive myocardial atrophy and fibrofatty replacement.
- Electrocardiograms (ECGs) and signal-averaged ECGs (SAECGs) are established, cost-effective diagnostic tools.
Purpose of the Study:
- To evaluate the diagnostic capability of ECGs and SAECGs in patients with ARVC.
- To correlate electrocardiographic findings with the extent of ARVC.
Main Methods:
- Analysis of ECGs and SAECGs from 205 ARVC patients.
- Comparison of QRS voltages in ARVC patients versus 120 healthy subjects.
- Identification of common electrocardiographic abnormalities.
Main Results:
- ECGs were abnormal in 74% and SAECGs positive in 60% of ARVC patients.
- Common abnormalities include QRS prolongation, T-wave inversion, and epsilon waves.
- Low QRS voltages were frequent in ARVC patients (p = 0.00001).
- Electrocardiographic abnormalities correlated with disease extent and ventricular involvement.
Conclusions:
- ECGs and SAECGs are valuable for diagnosing ARVC and assessing its extent.
- Abnormalities are frequent and correlate with disease severity, though no single pattern exists.
- A normal ECG does not rule out ARVC.
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