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Updated: Jun 23, 2026

Fertility Preservation in Patients with Severe Ovarian Dysfunction
Published on: March 25, 2021
A cost-effectiveness comparison of embryo donation with oocyte donation
Reginald Finger1, Carol Sommerfelt, Melanie Freeman
1National Embryo Donation Center, Knoxville, Tennessee 37934, USA. reg.finger@hotmail.com
Objective:
To compare the cost-effectiveness of embryo donation (ED) to that of oocyte donation (OD).
Design:
Calculation of cost-effectiveness ratios (costs per outcome achieved) using data derived from clinical practices.
Setting:
In vitro fertilization centers and embryo donation programs.
Patient(S):
Infertile couples undergoing oocyte donation or embryo donation.
Intervention(S):
Oocyte donation or embryo donation cycles.
Main Outcome Measure(S):
Cost-effectiveness ratios.
Result(S):
For a single cycle, ED is approximately twice as cost-effective as OD, with a cost-effectiveness ratio of $21,990 per live delivery compared to 40,600 dollars. When strategies of up to three cycles (to achieve one live delivery) are used, ED costs 13,505 dollars per live delivery compared to 31,349 dollars for OD.
Conclusion(S):
Cost-effectiveness is a compelling reason for infertile couples to consider embryo donation.
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