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Updated: Jun 23, 2026

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

The Microbe browser for comparative genomics.

Alexandre Gattiker¹, Christophe Dessimoz, Adrian Schneider

¹Swiss Institute of Bioinformatics, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.

Nucleic Acids Research

|May 2, 2009

Summary

This summary is machine-generated.

The Microbe browser offers integrated comparative microbial genomics data for all sequenced bacterial and archaeal genomes. This daily updated web server provides easy access to comprehensive genomic information and predictions.

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Last Updated: Jun 23, 2026

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

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Published on: January 13, 2017

Area of Science:

Microbial Genomics
Bioinformatics
Comparative Genomics

Background:

Comparative genomics facilitates understanding microbial evolution and function.
Access to integrated, up-to-date microbial genomic data is crucial for researchers.
Existing resources may lack comprehensive integration or daily updates.

Purpose of the Study:

To present the Microbe browser, a novel web server for comparative microbial genomics.
To provide an integrated platform for accessing and analyzing microbial genomic data.
To offer daily updated information on bacterial and archaeal genomes.

Main Methods:

Integration of data from GenBank, RefSeq, UniProt, InterPro, Gene Ontology, and OMA.
Inclusion of gene predictions from five distinct software packages.
Development of an interactive website utilizing Ensembl software architecture.
Daily updates from source databases to ensure data freshness.

Main Results:

The Microbe browser provides a comprehensive, integrated view of microbial genomic data.
It includes all completely sequenced bacterial and archaeal genomes.
Gene predictions from multiple sources are available alongside curated genomic information.
An interactive and user-friendly interface enhances data exploration.

Conclusions:

The Microbe browser serves as a valuable resource for comparative microbial genomics research.
Its daily updates and integrated data enhance its utility for scientists.
Programmatic access via the OMA API further extends its applicability.