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Anorexia Nervosa

Anorexia Nervosa

Anorexia nervosa is a complex and severe eating disorder characterized by an intense fear of weight gain, an unrelenting pursuit of thinness, and a distorted body image. It often leads to dangerously low body weight relative to an individual's age and height. This disorder is marked by significant physical and psychological consequences, making it one of the most life-threatening psychiatric illnesses.
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...

Bulimia Nervosa

Bulimia Nervosa

Bulimia nervosa is a complex and severe eating disorder characterized by a cyclical pattern of binge-and-purge eating pattern. It generally involves an episode of binge eating, followed by compensatory behaviors such as vomiting, excessive exercise, laxative use, or fasting, to prevent weight gain. Despite often maintaining a normal weight, individuals with bulimia are intensely preoccupied with their body image and harbor an overwhelming fear of gaining weight. This can contribute to the...

Binge Eating Disorders

Binge Eating Disorders

Binge eating disorder is a significant mental health condition characterized by recurrent episodes of excessive food consumption within a short period, accompanied by a perceived loss of control over eating behavior. Unlike occasional overeating, binge eating disorder is marked by distressing emotions such as guilt, shame, and anxiety following binge episodes. The disorder affects individuals across different ages and backgrounds, with profound implications for physical and psychological...

Sex Linked Disorders

Sex Linked Disorders

Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.

Nondisjunction

Nondisjunction

Nondisjunction is the failure of homologous chromosomes or sister chromatids to separate correctly and move to the opposite poles of the cells. This produces daughter cells with abnormal chromosome numbers. Nondisjunction is common during anaphase I or anaphase II of meiosis. Mutations in synaptonemal complex proteins that attach homologous chromosomes increase the chances of nondisjunction in anaphase I of meiosis I. In contrast, mutations in topoisomerases and condensins that hold sister...

Nondisjunction

Nondisjunction

During meiosis, chromosomes occasionally separate improperly. This occurs due to failure of homologous chromosome separation during meiosis I or failed sister chromatid separation during meiosis II. In some species, notably plants, nondisjunction can result in an organism with an entire additional set of chromosomes, which is called polyploidy. In humans, nondisjunction can occur during male or female gametogenesis and the resulting gametes possess one too many or one too few chromosomes.

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Related Experiment Video

Updated: Jun 23, 2026

Assessing Activity-based Anorexia in Mice

Assessing Activity-based Anorexia in Mice

Published on: May 14, 2018

Anorexia nervosa in identical triplets.

M S Sokol¹, Anna K Carroll, Denise M Heebink

¹Creighton University School of Medicine, Omaha, NE, USA.

|May 2, 2009

Summary

This case report highlights the multifactorial causes of anorexia nervosa (AN) and the success of integrated treatment in identical triplets. It emphasizes addressing psychological, familial, and environmental factors for effective eating disorder recovery.

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Last Updated: Jun 23, 2026

Assessing Activity-based Anorexia in Mice

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Control of Eating Behavior Using a Novel Feedback System

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Published on: May 8, 2018

Area of Science:

Psychiatry
Genetics
Family Studies

Background:

Anorexia nervosa (AN) etiology is complex, involving genetic, environmental, psychological, and familial factors.
Understanding the interplay of these factors is crucial for effective treatment.
Twin and family studies provide insights into genetic and environmental contributions to AN.

Observation:

A rare case of 12-year-old identical female triplets simultaneously diagnosed with AN.
The triplets exhibited an overly close relationship and competitiveness, contributing to their eating disorder.
Family dynamics and group treatment approaches were noted as significant factors.

Findings:

Integrated treatment, including individual and family psychotherapy, nutritional counseling, and psychoeducation, proved successful.
Encouraging healthy competition and mutual support among the triplets facilitated treatment goal achievement.
Literature review on AN twin studies reinforces the understanding of genetic and environmental influences.

Implications:

This case underscores the necessity of a holistic approach in AN evaluation and treatment.
It highlights the importance of considering individual and familial dynamics in eating disorder recovery.
Findings contribute to understanding AN in genetically related individuals and families with multiple affected members.