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Comparison of two prognostic scores for patients with parotid carcinoma
Ademar Takahama1, Alvaro Sanabria, Gustavo Melo Benevides
1Department of Oral Diagnosis, Piracicaba Dental School, University of Campinas, Brazil. ademartjr@yahoo.com.br
Background:
Salivary glands present a wide diversity in histopathologic types and biologic behaviors, thus complicating the search for prognostic factors.
Methods:
We compared 2 prognostic scores that were previously published for patients with parotid carcinoma in a retrospective series of 175 patients treated in a single institution.
Results:
Cox multivariate analysis indicated clinical skin invasion, facial nerve function, and perineural growth as the most significant recurrent disease-related prognostic factors. According to the Vander Poorten score, 148 patients were divided into 4 groups, with the 5-year disease-free survival of 76%, 81%, 69%, and 35%, respectively. In the Carrillo's score, the patients were divided into 3 groups: low-risk, intermediate-risk, and high-risk, with the 5-year disease-free survival of 84%, 73%, and 34%, respectively.
Conclusion:
Carrillo's score showed more distinct survival curves, and determination of groups with a more favorable prognosis was difficult for both scores. Therefore, both scores were not totally reproducible for our group of patients.
