Related Experiment Video
Updated: Jun 23, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
Published on: December 9, 2015
Regression analysis of the symptoms
Josipa S Gruden-Pokupec1, Vladimir Gruden, Zeljko Orihovac
1Stomatological Policlinic, Zagreb, Croatia.
Abstract:
Stomatopyrosis of 'burning mouth' syndrome, in a narrower sense of definition, is a condition characterized by sensation of burning and heating in mouth, despite its normal mucosa. This research has been directed towards treatment of stomatopyrosis, putting emphasis on the implementation of psychopharmacotherapy and psychotherapy. The research was conducted on altogether 120 respondents suffering from stomatopyrosis. The respondents were divided into two equal groups: each one comprising 60 members. All the respondents were treated by means of a standard topical therapy. All the patients were assessed clinically and by means of psychological tests measuring depression and anxiety four times: once before the treatment, after one month, after two months and after four months since the beginning of the treatment. The acquired data were afterwards statistically processed. Our research led to the conclusion that stomatopyrosis occurs with elderly people, primarily women. Regarding their occupation, majority of the respondents were clerks, followed by retirees. The burning sensation in mouth was present with all the respondents, the dominating site being the lips, while the nature of sensation was reported as mostly unbearable. Anxiety, tension and stress tend to aggravate the symptoms. When grading the symptoms on VAS, i.e. visual analogous scale, the subjective assessment of symptoms was marked as 7-8 cm, which shows a high degree of burning sensation. According to our study, the quantity of saliva, which was at the beginning of the research slightly decreased, normalized after the treatment. Apart from the clinical investigation of stomatopyrosis, we applied Depression and Anxiety questionnaires. During the therapy, the results of the depression test have shown a decrease in depression (from 56.7% to 0.00%), which is particularly apparent in the group treated by autogenic training and in the first group of respondents, i.e. the one treated with antidepressants. The Anxiety tests have shown a higher percentage and intensity of anxiety with men (62.5%, as opposed to women - 32.5%) in the beginning, which has dropped to 7.5% with men during the treatment and 8.8% with women. Clinical presentation of stomatopyrosis has also apparently improved. This improvement in clinical symptoms and psychological condition of patients is statistically significant. On the basis of our research, we have concluded the following: the comorbidity of stomatopyrosis with the phenomena of anxiety and depression proves that, among other factors, there is a psychogenic aetiology of this disease. Further research should provide answers to the questions whether stomatopyrosis is a psychosomatic or a conversive disorder Antidepressants and anxiolytics have an important role in the therapy of stomatopyrosis. Autogenic training, which is a psychotherapeutic anxiolytic technique, is a therapy of choice for stomatopyrosis, which contributes not only to the elimination of oral complaints, but to the emotional rehabilitation of the patients as well.
Related Concept Videos
Regression Toward the Mean
Regression Analysis
In regression analysis, a regression equation is determined based on the line of best fit– a line that best fits the data points plotted in a graph. This line is also called the regression line. The algebraic equation for the regression line is called the regression equation. It is represented as:
Residuals and Least-Squares Property
If the observed data point lies above the line, the residual is positive, and the line underestimates the actual data value for y. If the observed data point lies below the line, the residual is negative, and the line overestimates the actual data value for y.
The process of fitting the best-fit...
Microsoft Excel: Regression Analysis
To perform regression...
Multiple Regression
Farmers can use multiple regression to determine the crop yield based on more than one factor, such as water availability, fertilizer, soil properties, etc. Here, the crop yield is the response or dependent variable as it depends on the other independent variables. The analysis requires the construction of a scatter plot...
Negative and Cognitive Symptoms of Schizophrenia
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...