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Related Concept Videos

Cirrhosis I: Introduction01:23

Cirrhosis I: Introduction

Cirrhosis is a chronic, irreversible liver disease characterized by the widespread replacement of healthy liver tissue with fibrotic scar tissue and the formation of regenerative nodules.Etiology of cirrhosisCirrhosis results from sustained liver injury that triggers progressive fibrosis and structural remodeling. The underlying causes are diverse, encompassing common and less frequent clinical conditions. Regardless of the origin, all causes lead to chronic inflammation, hepatocyte loss, and...
Hormonal Regulation of the Menstrual Cycle01:22

Hormonal Regulation of the Menstrual Cycle

The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH release.
The Mammary Glands01:12

The Mammary Glands

The female breast is a hemispheric projection of variable size positioned anterior to the pectoralis major and serratus anterior muscles. A fascia layer composed of dense, irregular connective tissue connects it to these muscles.
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Gonadal and Placental Hormones01:24

Gonadal and Placental Hormones

The gonads, namely the testes in males and the ovaries in females, are pivotal in producing gonadal hormones that orchestrate the intricate processes of sexual development and reproduction.
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Hormonal Regulation

The renin-aldosterone system is an endocrine system which guides the renal absorption of water and electrolytes, thus managing blood pressure and osmoregulation. Activation of the system begins in the kidneys with a small cluster of cells adjacent to the afferent and efferent blood vessels of the renal corpuscle. As the nephrons are filtering blood, juxtaglomerular cells monitor blood pressure. If they detect a decrease in pressure, they release the hormone renin into the bloodstream.
Hormonal Regulation01:40

Hormonal Regulation

Hormones regulate a significant portion of digestion through activation of the neuroendocrine system. The neuroendocrine system of digestion contains many different hormones all with multiple functions that are both, directly and indirectly, involved in digestion.

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Related Experiment Video

Updated: Jun 23, 2026

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
13:35

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction

Published on: May 17, 2024

Current concepts in gynaecomastia.

H L Devalia1, G T Layer

  • 1Royal Surrey County Hospital NHS Trust and University of Surrey, Egerton Road, Guildford. hareshdevalia@doctors.org.uk

The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
|May 5, 2009
PubMed
Summary

Gynaecomastia, a common breast condition, requires thorough evaluation and individualized treatment. Management options include medical or surgical interventions based on patient symptoms, underlying causes, and disease progression.

Related Experiment Videos

Last Updated: Jun 23, 2026

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
13:35

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction

Published on: May 17, 2024

Area of Science:

  • Endocrinology
  • General Surgery
  • Oncology

Background:

  • Gynaecomastia is a prevalent breast condition in men.
  • Accurate diagnosis necessitates comprehensive patient history, physical examination, and targeted investigations.
  • Management strategies should address the underlying etiology, symptoms, and the condition itself.

Purpose of the Study:

  • To outline the diagnostic and therapeutic approaches for managing gynaecomastia.
  • To delineate the indications for medical and surgical interventions.
  • To emphasize the importance of patient counseling in the management of gynaecomastia.

Main Methods:

  • Review of clinical guidelines and literature on gynaecomastia management.
  • Analysis of diagnostic criteria including history, examination, and investigations.
  • Evaluation of treatment modalities: medical and surgical options.

Main Results:

  • Individualized treatment plans are crucial for effective gynaecomastia management.
  • Medical therapy is often preferred for symptomatic cases.
  • Surgical intervention is indicated for treatment failures, drug side effects, malignancy concerns, or significant cosmetic distress.

Conclusions:

  • A systematic approach to gynaecomastia, integrating medical and surgical expertise, ensures optimal patient outcomes.
  • Pre-operative counseling is vital for managing patient expectations and minimizing potential litigation.
  • Further research may refine treatment algorithms for specific subgroups of patients with gynaecomastia.