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The Early Endosome: Endocytosis of Transferrin01:28

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Related Experiment Video

Updated: Jun 23, 2026

Immunofluorescence to Monitor the Cellular Uptake of Human Lactoferrin and its Associated Antiviral Activity Against the Hepatitis C Virus
06:28

Immunofluorescence to Monitor the Cellular Uptake of Human Lactoferrin and its Associated Antiviral Activity Against the Hepatitis C Virus

Published on: October 1, 2015

[Lactoferrin: a multifunctional protein].

Annick Pierce1, Dominique Legrand, Joël Mazurier

  • 1Unité de Glycobiologie Structurale et Fonctionnelle, CNRS UMR 8576, Université des Sciences et des Technologies de Lille, IFR 147, 59655 Villeneuve d'Ascq Cedex, France. annick.pierce@univ-lille1.fr

Medecine Sciences : M/S
|May 5, 2009
PubMed
Summary
This summary is machine-generated.

Lactoferrin (Lf) is a multifunctional protein crucial for innate immunity. It exhibits antimicrobial, anti-inflammatory, and anti-cancer effects, showing promise for health and nutritional applications.

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Last Updated: Jun 23, 2026

Immunofluorescence to Monitor the Cellular Uptake of Human Lactoferrin and its Associated Antiviral Activity Against the Hepatitis C Virus
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Area of Science:

  • Biochemistry
  • Immunology
  • Molecular Biology

Background:

  • Lactoferrin (Lf) is an iron-binding glycoprotein in the transferrin family.
  • It is secreted by glandular cells and neutrophils, released during inflammation.

Purpose of the Study:

  • To highlight the multifunctional nature of lactoferrin.
  • To explore its diverse biological activities and potential applications.

Main Methods:

  • Literature review of in vivo studies and clinical trials.
  • Analysis of lactoferrin's molecular interactions and biological functions.

Main Results:

  • Lactoferrin possesses direct antimicrobial activity against various pathogens.
  • It demonstrates significant anti-inflammatory, immunomodulatory, and anti-cancer effects.
  • Lf plays a role in iron delivery and bone growth.

Conclusions:

  • Lactoferrin is a key component of the innate immune system with broad-spectrum protective effects.
  • Its diverse functions, including antimicrobial and immunomodulatory properties, make it a promising candidate for health and nutritional applications.