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[Final size attained in type 1 diabetes children]

R Galera Martínez1, E García García, M D Gámez Gómez

  • 1Unidad de Endocrinología Infantil, Servicio de Pediatría, Hospital Torrecárdenas, Almería, España. r.galera@yahoo.es

Anales De Pediatria (Barcelona, Spain : 2003)
|May 5, 2009
PubMed

Insights

Children with type 1 diabetes mellitus experienced growth reduction, especially prepubertal boys. Poorer metabolic control, indicated by glycated haemoglobin, correlated with reduced height gain in both sexes.

Area of Science:

  • Pediatric Endocrinology
  • Metabolic Disorders
  • Growth and Development

Context:

  • Type 1 diabetes mellitus (T1DM) diagnosis in childhood can impact growth.
  • Understanding final height and height gain is crucial for long-term health outcomes.

Purpose:

  • To evaluate final height and height gain in children with T1DM relative to target height.
  • To analyze the relationship between growth parameters and variables like metabolic control (HbA1c), insulin dose, and BMI.

Summary:

  • Children with T1DM were initially taller than average, but experienced growth reduction during disease progression, particularly prepubertal boys.
  • Final height was slightly below average in boys and similar to the general population in girls. Height gain was less in boys.
  • Mean glycated haemoglobin (HbA1c) was the sole significant predictor of reduced height gain, with a 2 cm reduction for every 1% increase.

Impact:

  • Highlights the negative impact of T1DM and suboptimal metabolic control on growth in children.
  • Provides valuable data for pediatric endocrinologists managing T1DM, emphasizing the importance of glycemic control for growth.
  • Informs clinical practice regarding growth monitoring and management strategies for children with T1DM.
Abstract

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