Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

IR Spectrometers

IR Spectrometers

There are two main infrared (IR) spectrophotometers: dispersive IR spectrometers and Fourier transform infrared (FTIR) spectrometers. In a dispersive IR spectrometer, a beam of infrared radiation produced by a hot wire is divided into two parallel equal-intensity beams using mirrors. One beam passes through the sample, while another is a reference beam. The beams then move through the monochromator, which separates the radiations into a continuous spectrum of different frequencies. The...

Attenuated Total Reflectance (ATR) Infrared Spectroscopy: Overview

Attenuated Total Reflectance (ATR) Infrared Spectroscopy: Overview

Attenuated total reflectance (ATR) infrared spectroscopy is a powerful analytical technique used to study the composition of materials. It is widely employed in chemistry, materials science, forensic science, and other fields where sample characterization is required. ATR has several advantages over traditional transmission IR spectroscopy, including the requirement of little to no sample preparation and the ability to analyze a wide range of samples.
The ATR process begins by directing a beam...

Total Internal Reflection Fluorescence Microscopy

Total Internal Reflection Fluorescence Microscopy

Total internal reflection fluorescence microscopy or TIRF is an advanced microscopic technique used to visualize fluorophores in samples close to a solid surface with a higher refractive index, such as a glass coverslip. TIRF only allows fluorophores in proximity to the solid surface to be excited. When light from a medium with a lower refractive index (such as air) hits the glass coverslip at a critical angle, the light undergoes total internal reflection stead of passing through the glass.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

2025 Update of the Taiwan Expert Consensus on Hormone Receptor-Positive Metastatic Breast Cancer Management.

Journal of breast cancer·2026

Same author

Dynamic circulating biomarkers for predicting adverse events in PRaG therapy: a pooled analysis and model construction from PRaG series clinical trials.

Cancer immunology, immunotherapy : CII·2026

Same author

Targeted isolation of new di/trinormonoterpenoid glucosides as cyclooxygenase-2 inhibitors from Periplocae Cortex using molecular networking.

Fitoterapia·2025

Same author

Multimodal radiomic analysis to determine high-Consistency prognostic phenotypes associated with epidermal growth factor receptor mutations in non-small cell lung cancer brain metastases.

European journal of radiology·2025

Same author

Denosumab combined with immunotherapy, radiotherapy, and granulocyte-macrophage colony-stimulating factor for the treatment of metastatic nasopharyngeal carcinoma: A case report.

World journal of clinical oncology·2025

Same author

C<sub>21</sub> steroidal glycosides from the root bark of <i>Periploca sepium</i> and their NO production inhibitory and cytotoxic activity.

Natural product research·2023

Search research articles

Related Experiment Video

Updated: Jun 23, 2026

Implementation of a Reference Interferometer for Nanodetection

Implementation of a Reference Interferometer for Nanodetection

Published on: April 26, 2014

Small-displacement sensing system based on multiple total internal reflections in heterodyne interferometry.

Shinn-Fwu Wang¹, Ming-Hung Chiu, Wei-Wu Chen

¹Department of Electronic Engineering, Ching Yun University, No. 229, Chien-Hsin Road, Jhongli City, Taoyuan 320, Taiwan. sfwang@cyu.edu.tw

|May 5, 2009

Summary

This study introduces a novel small-displacement sensing system using heterodyne interferometry and multiple total internal reflections. The system achieves high resolution and sensitivity by measuring phase difference variations for precise real-time measurements.

More Related Videos

A Multimodal Wide-Field Fourier-Transform Raman Microscope

A Multimodal Wide-Field Fourier-Transform Raman Microscope

Published on: December 30, 2025

Fiber Optic Distributed Sensors for High-resolution Temperature Field Mapping

Fiber Optic Distributed Sensors for High-resolution Temperature Field Mapping

Published on: November 7, 2016

Related Experiment Videos

Last Updated: Jun 23, 2026

Implementation of a Reference Interferometer for Nanodetection

Implementation of a Reference Interferometer for Nanodetection

Published on: April 26, 2014

A Multimodal Wide-Field Fourier-Transform Raman Microscope

A Multimodal Wide-Field Fourier-Transform Raman Microscope

Published on: December 30, 2025

Fiber Optic Distributed Sensors for High-resolution Temperature Field Mapping

Fiber Optic Distributed Sensors for High-resolution Temperature Field Mapping

Published on: November 7, 2016

Area of Science:

Optics and Photonics
Metrology and Measurement Science

Background:

Accurate measurement of small displacements is crucial in various scientific and industrial applications.
Traditional interferometry methods face limitations in sensitivity and resolution for micro-scale displacement detection.

Purpose of the Study:

To propose and demonstrate a novel small-displacement sensing system.
To enhance sensitivity and resolution in displacement measurement using optical principles.

Main Methods:

Utilizing heterodyne interferometry combined with the principle of total internal reflection (TIR).
Employing a parallelogram prism to increase the number of TIR events.
Measuring the phase difference variation between s- and p-polarization states induced by TIR.

Main Results:

Achieved a theoretical resolution better than 0.417 nm for displacement sensing.
Demonstrated high sensitivity and real-time measurement capabilities.
Validated the feasibility of the proposed sensing system.

Conclusions:

The proposed system offers a promising approach for high-resolution, high-sensitivity small-displacement sensing.
The integration of multiple TIRs in heterodyne interferometry significantly improves measurement performance.
The method is suitable for applications requiring precise real-time displacement monitoring.