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Brain magnetic resonance findings in infective endocarditis with neurological complications

Asako Azuma1, Keiko Toyoda, Toshihiro O'uchi

  • 1Department of Radiology, Kameda Medical Center, Kamogawa, 296-8602, Japan. asakonemurinomori@yahoo.co.jp

Japanese Journal of Radiology
|May 5, 2009
PubMed
Abstract

Insights

Diagnosing infective endocarditis is challenging due to vague symptoms. Magnetic resonance imaging (MRI) reveals diverse intracranial abnormalities, aiding early diagnosis in patients with neurological complications.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Radiology

Background:

  • Infective endocarditis diagnosis is often delayed by nonspecific symptoms.
  • Neurological complications are common in infective endocarditis.
  • Intracranial abnormalities on MRI are key indicators.

Purpose of the Study:

  • To review intracranial magnetic resonance imaging (MRI) findings in patients with infective endocarditis and neurological complications.
  • To correlate MRI findings with clinical presentation and outcomes.

Main Methods:

  • Retrospective review of 14 patients with infective endocarditis and neurological complications (August 2004 - August 2006).
  • Analysis of brain MRI scans, causative bacteria, and neurological symptoms.
  • Focus on specific MRI findings like embolization, hemorrhage, and abscess.

Main Results:

  • 13 out of 14 patients exhibited intracranial abnormalities on MRI.
  • Common findings included embolization (10 patients), hemorrhage (3), abscess (3), and encephalitis (2).
  • Unique 'bull's-eye-like' lesions were observed in 4 patients, often on T2*-weighted imaging.

Conclusions:

  • MRI reveals a spectrum of intracranial abnormalities in infective endocarditis.
  • Prompt brain MRI, especially T2*-weighted imaging, is crucial for early diagnosis.
  • Consider infective endocarditis in patients with unexplained fever and neurological deficits.

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