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Ocular involvement in sarcoidosis
Leyla S Atmaca1, Pelin Atmaca-Sönmez, Aysun Idil
1Department of Ophthalmology, Faculty of Medicine, Ankara University, Ankara, Turkey. leylaatmaca@ttmail.com
Ocular Immunology and Inflammation
|May 5, 2009
Summary
Ocular sarcoidosis affects 12.9% of patients, with combined anterior and posterior segment disease being most common. This study evaluated ocular manifestations in Turkish sarcoidosis patients.
Area of Science:
- Ophthalmology
- Rheumatology
- Pulmonology
Background:
- Sarcoidosis is a multisystem inflammatory disease of unknown etiology.
- Ocular involvement is a frequent manifestation of sarcoidosis, impacting visual prognosis.
Purpose of the Study:
- To determine the prevalence and patterns of ocular involvement in Turkish patients diagnosed with sarcoidosis.
Main Methods:
- A cross-sectional study involving 139 Turkish patients with sarcoidosis.
- Ocular involvement was assessed using clinical examination, color photography, and fluorescein angiography in suspected cases.
Main Results:
- Ocular manifestations were observed in 12.9% of the patients studied.
- Among those with ocular sarcoidosis, the most frequent pattern was combined anterior and posterior segment involvement (39%).
- Other patterns included isolated anterior (28%), isolated posterior (11%), conjunctival (16.7%), and eyelid (5.6%) involvement. No significant correlation was found between radiological staging and ocular disease.
Conclusions:
- Combined anterior and posterior segment involvement represents the most common ocular manifestation of sarcoidosis in this cohort.
- Early detection and management of ocular sarcoidosis are crucial for preserving vision.
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