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Updated: Jun 23, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Post-partum mental disorders in Sagamu.
P O Adefuye1, T A Fakoya, O L Odusoga
1Department of Obstetrics and Gynaecology, Obafemi Awolowo College of Health Sciences, Olabisi Onabanjo University, Sagamu, Ogun State, Nigeria.
Postpartum mental illness affects 2.9 per 1000 births, often occurring in younger, first-time mothers. Family history and marital issues are significant contributing factors to these conditions.
Area of Science:
- Obstetrics and Gynecology
- Psychiatry
- Public Health
Background:
- Pregnancy and childbirth can trigger new or recurring postpartum mental disorders.
- These conditions are often underreported in clinical practice.
- Understanding incidence and contributing factors is crucial for maternal mental health.
Purpose of the Study:
- To determine the incidence of postpartum mental disorders.
- To identify patterns of presentation.
- To explore commonly associated etiological factors.
Main Methods:
- Retrospective descriptive study design.
- Data collected from Olabisi Onabanjo University, Sagamu, Nigeria.
- Analysis of 9085 deliveries over the study period.
Main Results:
- An incidence of 2.9 per 1000 births for puerperal mental illness was recorded.
- The mean age of affected mothers was 27.3 years, with a mean parity of 2.3.
- The mean interval from delivery to presentation was 11.5 days, with a mean hospitalization of 12.4 days.
Conclusions:
- The incidence of postpartum mental illness in this practice is 2.9 per 1000 births.
- Primiparity and young maternal age were prevalent in the study group.
- Family history of psychiatric disorders and marital disharmony are significant etiological factors.
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