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Related Concept Videos

Local Anesthetics: Clinical Application as Spinal Anesthesia01:11

Local Anesthetics: Clinical Application as Spinal Anesthesia

Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
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Skeletal muscle relaxants are used to relax muscle tone and alleviate painful muscle contractions. However, the choice of skeletal muscle relaxants depends on the duration of the surgical procedure in order to minimize potential side effects. Skeletal muscle relaxants like neuromuscular blocking agents [NMBAs] are commonly employed as adjuvants alongside general anesthetics in clinical settings. NMBAs are also used to maintain controlled ventilation during surgery of the larynx or pharynx as...
Local Anesthetics: Clinical Application as Epidural Anesthesia01:29

Local Anesthetics: Clinical Application as Epidural Anesthesia

Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
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Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
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General Anesthesia: Overview01:24

General Anesthesia: Overview

Anesthesia is a medical procedure that uses drugs for CNS suppression to enable painless surgeries and procedures. The selection of anesthetics is influenced by their pharmacokinetic properties, side effects, and patient characteristics. Various types of anesthesia include general, local, regional, spinal, and inhalational.
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Updated: Jun 23, 2026

Du-Moxibustion in a Mouse Model of Ankylosing Spondylitis
04:47

Du-Moxibustion in a Mouse Model of Ankylosing Spondylitis

Published on: October 27, 2023

Ankylosing spondylitis: recent developments and anaesthetic implications.

L J Woodward1, P C A Kam

  • 1Department of Anaesthetics, University of Sydney, Royal Prince Alfred Hospital, Camperdown, NSW 2050, Australia.

Anaesthesia
|May 6, 2009
PubMed
Summary
This summary is machine-generated.

Ankylosing spondylitis poses anesthetic challenges, including difficult airways and potential complications. Awake fiberoptic intubation and neurophysiological monitoring are key strategies for safe peri-operative management.

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Du-Moxibustion in a Mouse Model of Ankylosing Spondylitis
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Area of Science:

  • Anesthesiology
  • Rheumatology
  • Neurosurgery

Background:

  • Ankylosing spondylitis presents anesthetic challenges due to potential difficult airways, cardiovascular/respiratory issues, and medication side effects.
  • Increased risk of peri-operative neurological complications is a concern for patients with ankylosing spondylitis.
  • Current medical management involves anti-tumour necrosis factor-alpha agents, which may increase wound infection risk.

Purpose of the Study:

  • To review the significant anesthetic issues encountered in patients with ankylosing spondylitis.
  • To highlight the importance of understanding these challenges for effective peri-operative planning.
  • To discuss optimal anesthetic strategies for managing ankylosing spondylitis patients.

Main Methods:

  • Review of anesthetic considerations for ankylosing spondylitis.
  • Discussion of airway management techniques, including awake fiberoptic intubation.
  • Consideration of neurophysiological monitoring (somatosensory and motor evoked potentials) for cervical spine surgery.

Main Results:

  • Awake fiberoptic intubation is recommended for patients with potentially difficult airways.
  • Neurophysiological monitoring is advised for surgeries involving cervical spine deformity.
  • Anti-tumour necrosis factor-alpha agents improve disease management but carry a risk of increased wound infection.

Conclusions:

  • Anesthetists must understand the multifaceted challenges of ankylosing spondylitis for safe patient care.
  • Careful pre-operative assessment and planning are crucial for managing airway, cardiovascular, respiratory, and neurological risks.
  • Appropriate anesthetic techniques and monitoring can mitigate peri-operative complications in ankylosing spondylitis patients.