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Updated: Jun 23, 2026
03:23
Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis
Published on: May 10, 2024
Steroid utilization in eosinophilic jejunitis: beneficial or harmful?
Cemil Caliskan1, Ozgur Firat, Avni Can Karaca
1Department of General Surgery, Division of Proctology, Ege University School of Medicine, Bornova, 35100, Izmir, Turkey. cemil.caliskan@ege.edu.tr
Langenbeck'S Archives of Surgery
|May 7, 2009
Summary
Steroid therapy may be effective for eosinophilic jejunitis, a rare intestinal disorder. This study evaluates its impact on patients with this condition, offering insights for clinical practice.
Area of Science:
- Gastroenterology
- Immunology
Background:
- Eosinophilic jejunitis is a rare gastrointestinal disorder of unknown etiology.
- It involves eosinophilic infiltration of the small intestine, leading to symptoms like abdominal pain and obstruction.
Observation:
- A case of eosinophilic jejunitis presented with small bowel obstruction, complicated by perforation.
- Diagnosis was confirmed during a prior surgical procedure, with symptoms masked by medications.
Findings:
- Eosinophilic jejunitis typically affects individuals aged 30-50.
- Common symptoms include abdominal pain, obstructive symptoms, and weight loss.
- Current management strategies suggest avoiding resection unless absolutely necessary.
Implications:
- Eosinophils may directly contribute to gastrointestinal tract wall damage.
- Limited literature supports steroid therapy for eosinophilic jejunitis.
- This review discusses the therapeutic effects of steroids in managing eosinophilic jejunitis.
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