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Published on: July 5, 2017
Prenylflavonols from the leaves of Macaranga sampsonii
Xiaohua Li1, Liangxiong Xu, Ping Wu
1Key Labotatory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou, China.
Abstract:
Four novel prenylflavonols, macaranones A-D (1-4), were isolated from the leaves of Macaranga sampsonii. Their structures were elucidated on the basis of spectroscopic data. Macaranones C (3) and D (4) represent first two examples of flavonols having an unusual peltogynoid skeleton which is formed from a 2'-geranylflavonol by cyclization between 3-OH and C-1'' of the 2'-geranyl substituent of the flavonol. Compounds 1-4 were evaluated for the cytotoxicity against several human cancer cell lines.
