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Using Modified Synthetic Oligonucleotides to Assay Nucleic Acid-Metabolizing Enzymes
Published on: July 5, 2024
NMR assignment of polymerase beta labeled with 2H, 13C, and 15N in complex with substrate DNA
Geoffrey A Mueller1, Eugene F DeRose, Thomas W Kirby
1National Institute of Environmental Health Sciences, Research Triangle Park, NC 23455, USA.
Biomolecular NMR Assignments
|May 8, 2009
Abstract:
DNA polymerase beta is a multifunctional enzyme involved in base excision repair of nuclear DNA invertebrate cells. We present here the first assignments of the full-length protein (335 residues, 39 kDa) in the presence of a double gap--double hairpin DNA (22 nucleotides, 7 kDa).

