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Related Experiment Video

Updated: Jun 23, 2026

Quantification of Atherosclerosis in Mice

Quantification of Atherosclerosis in Mice

Published on: June 12, 2019

Genetic variation and atherosclerosis.

Erik Biros¹, Mirko Karan, Jonathan Golledge

¹Vascular Biology Unit, School of Medicine, James Cook University, Townsville, QLD 4811, Australia.

Current Genomics

|May 9, 2009

Summary

This summary is machine-generated.

Family history of atherosclerosis increases cardiovascular events. Genetic variations like polymorphisms influence risk factors, impacting disease development and progression.

Keywords:

Atherosclerosis genetic polymorphism risk factors.

More Related Videos

A Human Ex Vivo Atherosclerotic Plaque Model to Study Lesion Biology

A Human Ex Vivo Atherosclerotic Plaque Model to Study Lesion Biology

Published on: May 6, 2014

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Last Updated: Jun 23, 2026

Quantification of Atherosclerosis in Mice

Quantification of Atherosclerosis in Mice

Published on: June 12, 2019

A Human Ex Vivo Atherosclerotic Plaque Model to Study Lesion Biology

A Human Ex Vivo Atherosclerotic Plaque Model to Study Lesion Biology

Published on: May 6, 2014

Area of Science:

Cardiovascular Genetics
Atherosclerosis Research

Background:

Family history of atherosclerosis is a significant predictor of cardiovascular events.
Genetic factors play a crucial role in the inheritance patterns of atherosclerosis.
Understanding these genetic underpinnings is key to managing cardiovascular risk.

Purpose of the Study:

To review current research on the role of genetic polymorphisms in atherosclerosis.
To highlight how genetic variations influence atherosclerosis risk factors.
To provide examples of genetic studies in atherosclerosis.

Main Methods:

Literature review of genetic studies in atherosclerosis.
Analysis of research investigating genetic polymorphisms and their impact on risk factors.
Synthesis of findings from various genetic association studies.

Main Results:

Genetic variations, including common polymorphisms, are implicated in modulating key atherosclerosis risk factors.
These factors include plasma lipoprotein levels, inflammatory processes, and vascular calcification.
Specific examples of genetic polymorphisms and their associations are presented.

Conclusions:

Genetic polymorphisms are integral to the development and progression of atherosclerosis.
Understanding genetic contributions can refine risk assessment and therapeutic strategies for cardiovascular disease.
Further research into genetic variations is essential for personalized medicine approaches in cardiology.