Related Experiment Video
Updated: Jun 23, 2026

Quantification of Atherosclerosis in Mice
Published on: June 12, 2019
Genetic variation and atherosclerosis
Erik Biros1, Mirko Karan, Jonathan Golledge
1Vascular Biology Unit, School of Medicine, James Cook University, Townsville, QLD 4811, Australia.
Abstract:
A family history of atherosclerosis is independently associated with an increased incidence of cardiovascular events. The genetic factors underlying the importance of inheritance in atherosclerosis are starting to be understood. Genetic variation, such as mutations or common polymorphisms has been shown to be involved in modulation of a range of risk factors, such as plasma lipoprotein levels, inflammation and vascular calcification. This review presents examples of present studies of the role of genetic polymorphism in atherosclerosis.
Related Concept Videos
Pharmacogenetic Phenotypes: Alterations in Pharmacokinetics, Drug Targets and Biologic Milieu
Genetic Variation
Genes exist in different versions called alleles, which...
Mutation, Gene Flow, and Genetic Drift
Atherosclerosis I: Introduction
Pharmacogenomics: Identification of New Drug Targets
Principles of Pharmacogenetics: Types of Genetic Variants
