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Updated: Jun 23, 2026
07:54
Long-term Blood Pressure Measurement in Freely Moving Mice Using Telemetry
Published on: May 17, 2016
CIRCANNUAL VARIATION IN HUMAN DIASTOLIC BLOOD PRESSURE DURING CONSECUTIVE SOLAR CYCLES
R B Sothern1, G Cornélissen, G Katinas
1Halberg Chronobiology Center, University of Minnesota, Minneapolis, Minnesota, USA.
Scripta Medica
|May 9, 2009
Summary
This study explores long-term diastolic blood pressure rhythms in a healthy individual. Findings suggest potential circadecadal influences on yearly blood pressure variations, highlighting complex biological rhythms.
Area of Science:
- Chronobiology
- Human Physiology
- Time Series Analysis
Background:
- Diastolic blood pressure exhibits complex temporal variations.
- Understanding long-term rhythms is crucial for cardiovascular health insights.
Purpose of the Study:
- To investigate potential circadecadal modulations of circannual rhythms in diastolic blood pressure.
- To analyze a 35-year record of self-measured blood pressure data.
Main Methods:
- Utilized gliding spectra, one-way analysis of variance (ANOVA), and cosinor analysis.
- Data excluded periods of travel across time zones and illness.
- Analyzed monthly means from a 35-year self-measurement record.
Main Results:
- Circannual variation in diastolic blood pressure was inconsistently detected by statistical significance.
- Detection appeared dependent on solar cycle number and/or stage.
- A consistent one-year synchronization was observed across the entire dataset.
- Evidence suggests intermodulation between different frequency rhythms (e.g., circadecadal and circannual).
Conclusions:
- Diastolic blood pressure may exhibit multifrequency rhythms with intermodulations.
- Lower frequency rhythms (circadecadal) can influence outcomes in higher frequency rhythms (circannual).
- Long-term self-monitoring provides valuable data for understanding complex biological rhythms.
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