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THE RELATIONSHIP BETWEEN CIRCADIAN BLOOD PRESSURE VARIATION AND AGE ANALYSED FROM 7-DAY MONITORING
J Siegelová1, J Dušek, B Fišer
1Department of Functional Diagnostics and Rehabilitation, Faculty of Medicine, Masaryk University, Brno, Czech Republic.
Scripta Medica
|May 14, 2009
Summary
This study reveals that while average systolic and diastolic blood pressure increase with age, the daily variation in blood pressure peaks in middle age and declines thereafter. Heart rate showed no age-related changes.
Area of Science:
- Cardiology
- Gerontology
- Chronobiology
Background:
- Circadian blood pressure (BP) variation is a critical factor in cardiovascular health.
- Understanding age-related changes in BP patterns is essential for effective hypertension management.
Purpose of the Study:
- To investigate the relationship between age and circadian blood pressure (BP) variation.
- To analyze how age influences the mean BP and the amplitude of BP fluctuations.
Main Methods:
- Ambulatory BP monitoring was conducted for seven days in 187 subjects aged 20-77 years.
- Sinusoidal curve fitting was used to evaluate daily BP mean (M) and double amplitude (2A) for systolic BP (SBP), diastolic BP (DBP), and heart rate (HR).
Main Results:
- Mean SBP and DBP showed a linear increase with age.
- BP amplitude (2A) increased with age up to 35 years, peaked around 45 years, and then decreased.
- Heart rate (M and 2A) was found to be independent of age.
Conclusions:
- Mean BP levels rise with age, but the diurnal BP variation pattern changes significantly across the lifespan.
- The findings suggest distinct age-related trajectories for BP levels versus BP variability.
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