Related Experiment Video
Updated: Jun 23, 2026

A Coupled Experiment-finite Element Modeling Methodology for Assessing High Strain Rate Mechanical Response of Soft Biomaterials
Published on: May 18, 2015
Injuries from explosions: physics, biophysics, pathology, and required research focus
Howard R Champion1, John B Holcomb, Lee Ann Young
1Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA. hrchampion@aol.com
Explosion injuries, a leading cause of battlefield death, require better medical understanding and research. Focusing on penetrating fragment wounds and comprehensive strategies improves patient outcomes in military and civilian settings.
Area of Science:
- Trauma Surgery
- Blast Injury Research
- Military Medicine
Background:
- Explosions cause complex injuries, leading to battlefield deaths and terrorist attacks.
- Civilian medical knowledge of explosion injuries is limited, necessitating broader research.
- Understanding these injuries is crucial for prevention, mitigation, and consequence management.
Purpose of the Study:
- Provide insight into explosion injury complexities.
- Target research efforts toward primary prevention, mitigation, and consequence management.
- Enhance medical community knowledge for acute patient needs.
Main Methods:
- Review of cited works using MeSH terms.
- Analysis of combat trauma databases.
- Inclusion of authors' surgical experience in Iraq.
Main Results:
- Survivable explosion injuries are primarily penetrating fragment wounds.
- Blast physics mechanisms are substantiated by data from Iraq and Afghanistan.
- Findings support targeted funding for research, training, and protective equipment.
Conclusions:
- A comprehensive approach includes primary prevention, injury mitigation, and consequence management.
- Recalibrating medical research focus will improve explosion injury management.
- Improved management has significant implications for civilian and military healthcare.
Related Concept Videos
Spinal Cord Injury ll: Pathophysiology
Cellular Injury I: Introduction
Burn Injuries
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
Cellular Injury II: Classification
Biological Effects of Radiation

