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Updated: Jun 23, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
[Geroprotectors: specific action or hormesis?]
Abstract:
In recent years, a number of nutrients and chemicals including antioxidants, vitamins, and hormones are widely advertised as "anti-aging" drugs ("geroprotectors"). It is usually believed that life-extending capacity of geroprotectors may be attributed to their specific anti-aging mechanisms, even without solid scientific evidence. Induction of the hormetic adaptive response in stressed organisms could be alternative explanation. The evidence that life-extending effects of anti-aging drugs may be due to hormetic-like response is discussed in this analytic review.
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