Related Experiment Video
Updated: Jun 23, 2026

Use of a Psychophysiological Script-driven Imagery Experiment to Study Trauma-related Dissociation in Borderline Personality Disorder
Published on: March 8, 2018
Trauma exposure and post-traumatic stress disorder in bipolar disorder
Hans-Jörg Assion1, Nils Brune, Nadja Schmidt
1Department of Psychiatry and Psychotherapy, LWL-Hospital, Ruhr-University Bochum, Alexandrinenstr. 1, 44791 Bochum, Germany. h.assion@gpz-lippe.de
Introduction:
There is a lack of data about post-traumatic stress disorder (PTSD) in European bipolar patients compared to the US-population. This study was conducted to ascertain the rates and types of traumatic events and PTSD in bipolar-I disorder.
Methods:
Euthymic bipolar patients were screened for lifetime diagnosis of PTSD using the Post-Traumatic Stress Diagnostic Scale and the Clinician Administered Post-traumatic Stress Disorder Scale.
Results:
A total of 74 patients (m = 30, f = 44) with diagnosis of bipolar-I disorder were assessed. 37 patients (50%) reported no trauma, 22 patients (29.7%) experienced traumatic events without diagnosis of PTSD and 15 patients (20.3%) had comorbid PTSD. Bipolar PTSD patients were at higher risk to be exposed to physical violence, parental disregard, alcohol dependence of parents, sexual assault by a family member or acquaintance. The number of siblings was higher and they had higher scores on the Hamilton Depression Rating Scale and the Global Assessment of Functioning Scale.
Conclusions:
Bipolar patients are more likely to experience traumatic events and PTSD is a relevant comorbid disorder. PTSD is associated with an increased illness severity of bipolar disorder.
Related Concept Videos
Bipolar Disorder
Post-traumatic Stress Disorder
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events, are a...
Mania and Antimanic Drugs: Overview
Borderline Personality Disorder
Genetic and Environmental Contributions
Borderline Personality...
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Dissociative Identity Disorder