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Updated: Jun 23, 2026

Frontal Disconnection for Treating Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Epilepsy (MOGHE) in the Frontal Lobe
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[Infantile cortical hyperostosis: case report].

A Ly-Ba1, O A Abdallah, S Ba-Diop

  • 1Service de Radiologie, CHNU de Dakar. salane@refer.sn

Le Mali Medical
|May 14, 2009
PubMed
Summary
This summary is machine-generated.

Infantile cortical hyperostosis (Caffey-Silverman disease) is a rare condition affecting infants. This case highlights its unusual presentation and the importance of considering antenatal diagnosis.

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Area of Science:

  • Pediatrics
  • Radiology
  • Genetics

Background:

  • Infantile cortical hyperostosis (ICH), also known as Caffey-Silverman disease, is a rare skeletal disorder primarily affecting infants.
  • It typically involves the long bones, but can affect flat bones, fascia, and muscles.

Observation:

  • A 3-month-old Mauritanian infant presented with recurrent osteitis of the left clavicle, snivelling, and left upper limb dysfunction.
  • Clinical examination revealed clavicular and mandibular swelling without fever.
  • Biological tests indicated inflammatory markers.

Findings:

  • Radiographs demonstrated cortical thickening in the left clavicle and mandible.
  • The case underscores the rarity and distinct age limitation of ICH.
  • The presentation was characterized by suggestive, albeit disconcerting, symptomatology at classical sites.

Implications:

  • This case emphasizes the diagnostic challenges and the importance of recognizing infantile cortical hyperostosis.
  • The possibility of antenatal diagnosis for ICH should be considered.
  • Further research into the genetic and environmental factors contributing to ICH is warranted.