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Updated: Jun 23, 2026

Evaluation of Cerebral Blood Flow Autoregulation in the Rat Using Laser Doppler Flowmetry
Published on: January 19, 2020
[Dynamics organ blood flow in rats in postnatal ontogenesis]
Abstract:
In the 4-, 13-, 30-, and 65- 90-day-old Wistar rats the voluminous blood flow rate was measured in liver, kidney, small intestine wall, and in the predominantly white gracilis muscle of femur. A LAKK-01 laser-Doppler flowmeter and its cutaneous (for kidney) and needle (for other organs) probes were used; they provided estimation of blood flow (per organ mass unit) to the tissue depth of about 1 mm. It has been found that the blood flow rates (per organ mass unit fall in liver, intestine, and even more in muscle, whereas increase in kidney, particularly for the first month of life. Calculations show that in adult rats as compared with the 4-day-old pups (with their mass exceeding 22 times) the blood flow to muscle, liver, intestine, and kidney should rise 14, 17, 18 and 43 times, respectively.
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