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Updated: Jun 23, 2026

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Fabrication of Electrochemical-DNA Biosensors for the Reagentless Detection of Nucleic Acids, Proteins and Small Molecules
Published on: June 1, 2011
Folding-based electrochemical DNA sensor fabricated on a gold-plated screen-printed carbon electrode
Weiwei Yang1, Jennifer Y Gerasimov, Rebecca Y Lai
1Department of Chemistry, University of Nebraska Lincoln, Lincoln, NE 68588-0304, USA.
Abstract:
Here we report a folding-based electrochemical DNA (E-DNA) sensor fabricated on a gold-plated screen-printed carbon electrode and show that the E-DNA sensor is not required to be fabricated on a relatively flat gold surface; the sensor works comparably well when fabricated on an electrodeposited gold film with a surface roughness factor of approximately 7.

