Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bioplastics01:27

Bioplastics

Bioplastics derived from microbial processes present a sustainable alternative to conventional petroleum-based plastics. Among these, polyhydroxyalkanoates (PHAs), particularly polyhydroxybutyrates (PHBs), have emerged as prominent candidates due to their biodegradability and biocompatibility. These polymers are synthesized by a variety of bacteria, such as Cupriavidus necator and Pseudomonas putida, which naturally accumulate PHAs as intracellular carbon and energy reserves, especially under...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Degradable Cationic Polyesters with Tunable Anion-Induced Upper Critical Solution Temperature Coacervation.

Biomacromolecules·2026
Same author

Author Correction: MAGE-A4/MAGE-A8-targeted TCR-based bispecific T cell engager in recurrent and/or refractory solid tumors: a phase 1 trial.

Nature medicine·2026
Same author

Mevalonate pathway activation in Ewing sarcoma reveals a 3D-specific synergy between statins and BCL-xL inhibition.

Molecular therapy. Oncology·2026
Same author

A multifactorial intervertebral disc degeneration model: Integrating inflammation, structural disruption, biomechanical parameters, and neural sensitization.

Bioengineering & translational medicine·2026
Same author

MAGE-A4/MAGE-A8-targeted TCR-based bispecific T cell engager in recurrent and/or refractory solid tumors: a phase 1 trial.

Nature medicine·2026
Same author

Evaluation of a GDNF-eluting nanofibrous PCL conduit in a mouse model of peripheral nerve injury.

RSC advances·2026
Same journal

Controlled Secondary Growth of CAU-1-NH<sub>2</sub> Membranes with Improved CO<sub>2</sub> Separation Performance.

Langmuir : the ACS journal of surfaces and colloids·2026
Same journal

Facile Fabrication and Stable Mechanism of a Microscale Heavy Calcium Carbonate Suspension.

Langmuir : the ACS journal of surfaces and colloids·2026
Same journal

Polycationic Biocidal Coatings: The Mechanism of Their Interaction with Cells.

Langmuir : the ACS journal of surfaces and colloids·2026
Same journal

Atomic-Scale Displacement in Ordered SmMnO<sub>3</sub> Nanoislands.

Langmuir : the ACS journal of surfaces and colloids·2026
Same journal

Vacancy Defect Modulated Interfacial Thermal Transport and Phonon Localization in AlGaN/GaN Heterojunctions.

Langmuir : the ACS journal of surfaces and colloids·2026
Same journal

Immobilization of Ytterbium via Polyphenol Chemistry on Implant Materials for Enhanced Cytocompatibility and Antibacterial Properties.

Langmuir : the ACS journal of surfaces and colloids·2026
See all related articles

Related Experiment Video

Updated: Jun 23, 2026

Two-Photon Polymerization 3D-Printing of Micro-scale Neuronal Cell Culture Devices
07:38

Two-Photon Polymerization 3D-Printing of Micro-scale Neuronal Cell Culture Devices

Published on: June 7, 2024

Three-dimensional biodegradable structures fabricated by two-photon polymerization.

Frederik Claeyssens1, Erol A Hasan, Arune Gaidukeviciute

  • 1Engineering Materials Department, Biomaterials and Tissue Engineering Group, Kroto Research Institute, University of Sheffield, Broad Lane, Sheffield S3 7HQ, United Kingdom. f.claeyssens@sheffield.ac.uk

Langmuir : the ACS Journal of Surfaces and Colloids
|May 14, 2009
PubMed
Summary
This summary is machine-generated.

Two-photon polymerization successfully created high-resolution, biodegradable scaffolds for tissue engineering. The novel material showed no negative impact on cell proliferation, indicating its potential for regenerative medicine applications.

More Related Videos

3D Printing and In Situ Surface Modification via Type I Photoinitiated Reversible Addition-Fragmentation Chain Transfer Polymerization
07:28

3D Printing and In Situ Surface Modification via Type I Photoinitiated Reversible Addition-Fragmentation Chain Transfer Polymerization

Published on: February 18, 2022

Three-dimensional Biomimetic Technology: Novel Biorubber Creates Defined Micro- and Macro-scale Architectures in Collagen Hydrogels
12:07

Three-dimensional Biomimetic Technology: Novel Biorubber Creates Defined Micro- and Macro-scale Architectures in Collagen Hydrogels

Published on: February 12, 2016

Related Experiment Videos

Last Updated: Jun 23, 2026

Two-Photon Polymerization 3D-Printing of Micro-scale Neuronal Cell Culture Devices
07:38

Two-Photon Polymerization 3D-Printing of Micro-scale Neuronal Cell Culture Devices

Published on: June 7, 2024

3D Printing and In Situ Surface Modification via Type I Photoinitiated Reversible Addition-Fragmentation Chain Transfer Polymerization
07:28

3D Printing and In Situ Surface Modification via Type I Photoinitiated Reversible Addition-Fragmentation Chain Transfer Polymerization

Published on: February 18, 2022

Three-dimensional Biomimetic Technology: Novel Biorubber Creates Defined Micro- and Macro-scale Architectures in Collagen Hydrogels
12:07

Three-dimensional Biomimetic Technology: Novel Biorubber Creates Defined Micro- and Macro-scale Architectures in Collagen Hydrogels

Published on: February 12, 2016

Area of Science:

  • Biomaterials Science
  • Tissue Engineering
  • Polymer Chemistry

Background:

  • Developing biocompatible and biodegradable materials is crucial for advanced tissue engineering applications.
  • Fabricating complex, high-resolution 3D structures requires precise and versatile fabrication techniques.
  • Biodegradable polymers offer promising alternatives to traditional materials for creating temporary tissue scaffolds.

Purpose of the Study:

  • To investigate the use of a specific biodegradable triblock copolymer for fabricating 3D structures via two-photon polymerization.
  • To assess the resolution and quality of the fabricated structures.
  • To evaluate the initial cytotoxicity of the material for potential tissue engineering applications.

Main Methods:

  • Utilized two-photon polymerization (TPP) for 3D fabrication.
  • Employed a biodegradable triblock copolymer: poly(epsilon-caprolactone-co-trimethylenecarbonate)-b-poly(ethylene glycol)-b-poly(epsilon-caprolactone-co-trimethylenecarbonate).
  • Used 4,4'-bis(diethylamino)benzophenone as the photoinitiator and conducted initial cytotoxicity tests on cell proliferation.

Main Results:

  • Successfully fabricated 3D structures with good quality and a resolution of four microns.
  • The biodegradable polymer-based scaffolds demonstrated high precision fabrication capabilities.
  • Initial cytotoxicity tests indicated no adverse effects on cell proliferation, suggesting good biocompatibility.

Conclusions:

  • Two-photon polymerization is a viable technology for fabricating high-resolution 3D structures from the studied biodegradable copolymer.
  • The material exhibits promising biocompatibility, making it suitable for tissue engineering scaffold development.
  • These findings support the potential of this approach for creating advanced biodegradable scaffolds for regenerative medicine.