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Related Concept Videos

Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...

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Related Experiment Video

Updated: Jun 23, 2026

Live Imaging of Antifungal Activity by Human Primary Neutrophils and Monocytes in Response to A. fumigatus
12:29

Live Imaging of Antifungal Activity by Human Primary Neutrophils and Monocytes in Response to A. fumigatus

Published on: April 19, 2017

Granuloma multiforme: a report from India.

Rashmi Kumari1, Devinder Mohan Thappa, Abhijit Chougule

  • 1Department of Dermatology and STD, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry-605 006, India.

Indian Journal of Dermatology, Venereology and Leprology
|May 15, 2009
PubMed
Summary
This summary is machine-generated.

Granuloma multiforme (GM) is a rare skin condition presenting as annular lesions. Diagnosis requires high suspicion and histopathology to distinguish it from leprosy and other granulomatous diseases.

Related Experiment Videos

Last Updated: Jun 23, 2026

Live Imaging of Antifungal Activity by Human Primary Neutrophils and Monocytes in Response to A. fumigatus
12:29

Live Imaging of Antifungal Activity by Human Primary Neutrophils and Monocytes in Response to A. fumigatus

Published on: April 19, 2017

Area of Science:

  • Dermatology
  • Pathology

Background:

  • Granuloma multiforme (GM) is an idiopathic reactive skin disorder.
  • It presents with annular lesions and is histologically characterized by necrobiosis and granulomas.
  • GM can be misdiagnosed as tuberculoid leprosy due to clinical similarities.

Observation:

  • A case of GM in a 70-year-old Indian male farmer is presented.
  • The patient exhibited asymptomatic annular papular lesions on photodistributed areas of the back and thighs.
  • Lesions were characterized as large, confluent rings.

Findings:

  • Histopathology is crucial for definitive diagnosis of GM.
  • Key histological findings include focal necrobiosis and histiocytic granulomas.
  • Differential diagnosis includes granuloma annulare, tuberculoid leprosy, actinic granuloma, and annular sarcoid.

Implications:

  • Accurate diagnosis of GM is essential to avoid misclassification with infectious diseases like leprosy.
  • Histopathological examination aids in differentiating GM from its mimics.
  • A high index of clinical suspicion is necessary for timely diagnosis of this rare condition.