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Updated: Jun 23, 2026

Studying Copper Nanoparticle-Induced Programmed Cell Death in Bacteria
Published on: May 16, 2025
Laboratory studies on biomachining of copper using Staphylococcus sp
Shinji Shikata1, Kurissery R Sreekumari, Kanavillil Nandakumar
1Joining and Welding Research Institute, Osaka University, Ibaraki, Japan.
This study shows that Staphylococcus sp. bacteria can effectively drill metallic surfaces, including perforating a thin copper film within seven days. This demonstrates bacteria
Area of Science:
- Microbiology
- Materials Science
- Biotechnology
Background:
- Bacterial corrosion of metals is a known phenomenon.
- Investigating novel applications of microorganisms in material processing is ongoing.
Purpose of the Study:
- To explore the potential of using Staphylococcus sp. for biomachining metallic surfaces.
- To quantify the extent of bacterial drilling on copper.
Main Methods:
- Exposure of copper coupons to Staphylococcus sp. cultures for up to 7 days.
- Microscopic observation and image analysis to determine pit area and volume.
- Perforation assay using a 2-micrometer copper thin film.
Main Results:
- Biomachined area and volume on copper coupons increased with exposure duration.
- Staphylococcus sp. successfully perforated a 2-micrometer copper thin film within 7 days.
- Controlled experiments with sterile medium showed no significant metal modification.
Conclusions:
- Bacteria, specifically Staphylococcus sp., can be utilized as a tool for machining metallic surfaces.
- This biomachining capability opens possibilities for novel microfabrication techniques.
- Further research can explore optimizing bacterial strains and conditions for precise metallic surface modification.
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