Related Experiment Video
Updated: Jun 23, 2026

Fluorescent Lateral Flow Immunoassay Based on Quantum Dots Nanobeads
Published on: June 28, 2024
Enhanced optical property of Au coated polystyrene beads for multi-color quantum dots encoding
Yuan-Cheng Cao1, Zhan Wang, Hai-Qiao Wang
1Key Laboratory of Biomedical Photonics of Ministry of Education - Wuhan National Laboratory for Optoelectronics, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei 430074, PR China.
Abstract:
A novel quantum dots (QDs) fluorescent encoding method was demonstrated in this paper by using Au coated polystyrene (Au @ PS) beads. In the experiments, Au nanoparticles were deposited onto the polystyrene bead to form a stable Au coating through Layer-by-Layer assembly, and the surface morphology of the Au @ PS beads was studied by Scanning Electronic Microscope (SEM). Furthermore, the QDs encoding abilities, including the loading of QDs, the anti-photo bleaching ability and the multi-color encoding feasibility were studied using Au @ PS beads. The QDs leakage from doped QDs encoded Au @ PS was also studied. This study shows that Au particles improve the QDs encoding performance and the QD-encoded Au @ PS beads are the ideal material for the optical encoding.

