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Updated: Jun 23, 2026

Monitoring Protein Adsorption with Solid-state Nanopores
Published on: December 2, 2011
Study of solid wall-liquid interaction on pressure-driven liquid transport through a nanopore in a membrane
Cunkui Huang1, Phillip Y K Choi, K Nandakumar
1Department of Mechanical Engineering, University of Alberta, Edmonton, Alberta T6G 2G8, Canada.
Abstract:
The effect of pore wall-liquid interaction on the liquid transport through a nanopore in a membrane was studied by an improved pressure-driven non-equilibrium molecular dynamics (NEMD) method. The NEMD results showed that pressures in the reservoirs were constant and were equal to the pressures externally exerted on the self-adjusting plates that drove the flow; pressures in the nanopore decreased monotonically in the stream-wise direction when the solid wall-liquid had weak or neutral interaction, but exhibited a different distribution pattern in the case of the solid wall-liquid exhibiting strong attractive interaction. The transport ability of the nanopore depended significantly on the pore wall-liquid interaction.
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