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Updated: Jun 23, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Non-surgical management of hormone-secreting pituitary tumors
Chirag G Patil1, Melanie Hayden, Laurence Katznelson
1Department of Neurosurgery, Stanford University School of Medicine, Stanford, California 94305, USA. chiragpatil@gmail.com
Abstract:
Hormone-secreting pituitary tumors account for about 30% of all pituitary tumors. Successful long-term management of patients with these tumors frequently requires a multimodality team approach. Given that the role and efficacy of neurosurgical resection of hormone-secreting pituitary tumors is well described, we focus this review on the other important treatment modalities that are becoming increasingly crucial in the management of acromegaly, Cushing's disease and prolactinomas. Medical management with standard and novel drugs as well as the role and effectiveness of radiation therapy and radiosurgery are discussed in detail.
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