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Published on: November 21, 2017
Integration of temperature-controlled requirements into pharmacy practice.
Ronald Ziance1, Chris Chandler, Rafik H Bishara
1College of Pharmacy, University of Southern Nevada, Henderson, USA.
Summary
Maintaining the quality of temperature-controlled drugs requires adherence to regulations and proper pharmacy practices. Pharmacists play a key role in ensuring drug efficacy through careful handling and patient education.
Area of Science:
- Pharmaceutical Sciences
- Supply Chain Management
- Regulatory Affairs
Background:
- Temperature-controlled prescription drugs require specific storage and handling protocols throughout the supply chain.
- Ensuring drug product quality from manufacturer to patient is critical for therapeutic efficacy.
Purpose of the Study:
- To outline Food and Drug Administration (FDA) regulations and professional guidelines for temperature-controlled drug storage, handling, and distribution.
- To describe pharmacy business practices that guarantee the dispensing of high-quality temperature-controlled drug products.
- To highlight patient education's role in maintaining drug quality.
Main Methods:
- Literature review of PubMed (1950-2007) using keywords related to drug stability and storage.
- Inclusion of data from FDA website, professional organizations, and meeting presentations.
- Independent data extraction and synthesis by authors.
Main Results:
- Pharmacists' business practices are crucial for ensuring drug quality, including sourcing quality drugs, proper handling, packaging, and patient information.
- Practices encompass quality agreements, appropriate receipt handling, patient packaging, information dissemination, and issue evaluation.
- These practices support the dispensing of high-quality temperature-controlled drugs and proper patient handling.
Conclusions:
- Complex supply chains present risks for temperature-controlled drugs deviating from recommended temperatures.
- Pharmacists can implement business practices to improve receipt, handling, and storage of these sensitive medications.
- Adoption of these practices enhances drug efficacy and patient safety.
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