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Protein quantification by mass spectrometry: is it ready for prime time?

Eleftherios P Diamandis1, Samir Hanash, Mary Lopez

  • 1Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, and University of Toronto, Toronto, Ontario, Canada.

Clinical Chemistry
|May 16, 2009
PubMed
Summary

No abstract available in PubMed .

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Tandem mass spectrometry, also known as MS/MS or MS2, is an analytical technique that employs two mass analyzers. Essentially it is a series of mass spectrometers that helps isolate a particular biomolecule and then helps study its chemical properties.
This technique helps gather information regarding the protein from which the peptide was obtained and to study the peptides’ amino acid sequence. Identifying peptides from a complex mixture is an important component of the growing field of...

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