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Factors that influence adherence with disease-modifying therapy in MS.
Katherine Treadaway1, Gary Cutter, Amber Salter
1Dept. of Neurology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75235, USA.
Journal of Neurology
|May 16, 2009
Summary
Forgetting injections is the primary reason for nonadherence in multiple sclerosis (MS) treatment. Optimizing adherence to disease-modifying therapies is crucial for effective MS management.
Area of Science:
- Neurology
- Pharmacology
Background:
- Injection therapies for chronic illnesses present challenges due to complexity and cost.
- Disease-modifying injection therapies for multiple sclerosis (MS) are often preventative with modest symptomatic effects.
Purpose of the Study:
- To identify factors influencing nonadherence to disease-modifying injection therapies in MS patients.
Main Methods:
- A multicenter, three-wave observational study using online surveys.
- Patients with MS were recruited from 17 neurology clinics.
Main Results:
- Nonadherence rates remained stable around 36-39% across three waves.
- Forgetting to administer medication was the most common reason for missing injections (58%).
- Other assessed factors included injection-site reactions, quality of life, patient perceptions, hope, depression, and support.
Conclusions:
- The study identifies key factors associated with nonadherence to MS injection therapy.
- Understanding these factors is essential for optimizing adherence and improving MS treatment outcomes.
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