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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Accessory Structures of the Skin: Sebaceous Glands01:21

Accessory Structures of the Skin: Sebaceous Glands

A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
Smallpox01:24

Smallpox

Smallpox is a severe contagious disease caused by the Variola major virus, a double-stranded DNA member of the Poxviridae family.Variola major transmission occurs primarily via inhalation of virus-laden droplets or direct contact with infectious scabs. The incubation period averages approximately seven days, although it may range from 7 to 17 days depending on the inoculum and host factors.Clinically, the prodromal phase is marked by an abrupt onset of high fever, malaise, headache, and myalgia.
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Chickenpox01:20

Chickenpox

Chickenpox is an acute, highly contagious disease caused by the varicella-zoster virus (VZV), a double-stranded DNA virus belonging to the Herpesviridae family. Its transmission occurs primarily through the inhalation of respiratory droplets or direct contact with vesicular fluid from skin lesions. The incubation period typically ranges from 10 to 21 days, during which the virus replicates and disseminates through sequential phases within the host. Although generally self-limiting in children,...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...

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Related Experiment Video

Updated: Jun 23, 2026

Clinical Examination Protocol to Detect Atypical and Classical Scrapie in Sheep
13:42

Clinical Examination Protocol to Detect Atypical and Classical Scrapie in Sheep

Published on: January 19, 2014

Scabies.

Prof Paul Johnstone1, Mark Strong

  • 1NHS/DH Yorkshire and Humberside, Leeds, UK.

BMJ Clinical Evidence
|May 19, 2009
PubMed
Summary
This summary is machine-generated.

This systematic review evaluates topical and oral scabies treatments, including benzyl benzoate, permethrin, and ivermectin. It assesses the effectiveness and safety of various scabies interventions for public health.

Related Experiment Videos

Last Updated: Jun 23, 2026

Clinical Examination Protocol to Detect Atypical and Classical Scrapie in Sheep
13:42

Clinical Examination Protocol to Detect Atypical and Classical Scrapie in Sheep

Published on: January 19, 2014

Area of Science:

  • Dermatology
  • Public Health
  • Evidence-Based Medicine

Background:

  • Scabies affects 300 million people globally, disproportionately impacting resource-poor nations.
  • Institutionalized communities in industrialized countries are also highly affected by scabies.

Purpose of the Study:

  • To systematically review the effects of topical and systemic scabies treatments.
  • To evaluate the effectiveness and safety of interventions for scabies management.

Main Methods:

  • Systematic review of literature up to October 2007.
  • Inclusion of systematic reviews, RCTs, and observational studies.
  • GRADE evaluation of evidence quality for scabies interventions.

Main Results:

  • Identified and evaluated evidence for topical treatments: benzyl benzoate, crotamiton, lindane, malathion, permethrin, and sulphur compounds.
  • Assessed oral treatment: ivermectin.
  • Included harms data from regulatory agencies like the FDA and MHRA.

Conclusions:

  • Presents information on the effectiveness and safety of key scabies interventions.
  • Provides a foundation for evidence-based treatment decisions in scabies management.
  • Highlights the need for updated reviews given the periodic nature of evidence updates.