Subarachnoid haemorrhage (spontaneous aneurysmal).

Area of Science:

• Neurosurgery
• Neurology
• Interventional Radiology

Background:

• Subarachnoid hemorrhage (SAH) is a critical neurological condition, often caused by ruptured aneurysms, presenting with severe headache.
• Spontaneous SAH constitutes approximately 5% of all stroke cases, with aneurysms being the primary cause in 85% of spontaneous cases.
• Diagnosis requires high clinical suspicion due to variable presentations, including atypical headache onset or absence.

Purpose of the Study:

• To systematically review and evaluate the effects of surgical treatments for patients with confirmed aneurysmal subarachnoid hemorrhage (aSAH).
• To compare the efficacy and safety of different surgical interventions for aSAH.

Main Methods:

• A systematic review was conducted, searching major medical databases up to October 2014.
• The review screened 47 records, with 14 full publications evaluated for inclusion.
• GRADE methodology was employed for evaluating evidence across six PICO combinations.

Main Results:

• The systematic overview identified and evaluated relevant studies on aSAH treatments.
• Evidence was synthesized to assess treatment outcomes.
• Specific comparisons were made regarding the effectiveness and safety of interventions.

Conclusions:

• The study categorized the efficacy of treatments for aSAH.
• A key comparison focused on the effectiveness and safety of endovascular coiling versus surgical clipping.