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Updated: Apr 21, 2026

Coherence between Brain Cortical Function and Neurocognitive Performance during Changed Gravity Conditions
Published on: May 23, 2011
Baroreflex and metaboreflex control of cardiovascular system during exercise in space
Massimo Pagani1, Paolo Pizzinelli, Silvia Beltrami
1UO Telematica per la Medicina e Medicina dello Sport, Ospedale "L. Sacco", Università degli Studi, Milano, Italy. mp@ctnv.unimi.it
Abstract:
This brief review summarizes current knowledge on the neural mechanisms of cardiovascular regulation during exercise in space, with specific emphasis on the role of the arterial baroreflex and the muscle metaboreflex, with the attendant modifications in autonomic nervous system activity, in determining the cardiovascular responses to exercise in microgravity conditions. Available data suggest that the muscle metaboreflex is enhanced during dynamic exercise in space and that the potentiation of the muscle metaboreflex affects the vagally mediated arterial baroreflex contribution to HR control.
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