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Updated: Jun 23, 2026

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
Published on: April 12, 2017
[What's new in 2008 in kidney cancer?]
V Phé1, M Rouprêt, E Lechevallier
1Service d'Urologie Hôpital Pitié-Salpétrière, Assistance Publique-Hôpitaux de Paris, Groupe Hospitalo-Universitaire Est, Faculté de médecine Pierre et Marie Curie, Université Paris VI, Paris, France.
Abstract:
The most innovating studies presented at the 2008 international conferences in the field of kidney cancer were selected. In localized kidney cancer, contrast-enhanced ultrasonography could be a new diagnostic tool. Many communications dealed with positive surgical margins and their consequences, and predictive factors of chronic kidney disease after nephrectomy. Robot-assisted laparoscopic nephrectomy seems to be a safe and effective technique. Mini-invasive treatments are promising. In metastatic kidney cancer, sunitinib was compared to IFN-alpha in first line treatment and survival data are now available. Everolimus could become the new standard after tyrosine kinase inhibitor failure.
Insights
Innovations in kidney cancer treatment include new diagnostic tools like contrast-enhanced ultrasonography and promising mini-invasive surgical options. For metastatic disease, updated survival data for sunitinib and the potential of everolimus after tyrosine kinase inhibitor failure were discussed.
Area of Science:
- Urology
- Oncology
Context:
- Highlights key advancements from 2008 international kidney cancer conferences.
- Focuses on both localized and metastatic kidney cancer research.
Purpose:
- To summarize innovative findings in kidney cancer diagnosis and treatment presented in 2008.
- To identify emerging trends and potential future standards of care.
Summary:
- Contrast-enhanced ultrasonography shows potential as a diagnostic tool for localized kidney cancer.
- Robot-assisted laparoscopic nephrectomy is presented as a safe and effective surgical option.
- Sunitinib survival data versus IFN-alpha in first-line treatment for metastatic kidney cancer is now available.
- Everolimus is emerging as a potential new standard treatment following tyrosine kinase inhibitor failure.
Impact:
- Provides a concise overview of cutting-edge kidney cancer research from 2008.
- Informs clinicians about novel diagnostic and therapeutic strategies.
- Identifies areas for future research and clinical application in kidney cancer management.
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