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Updated: Jun 23, 2026
05:25
Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing
Published on: August 14, 2019
A possible relationship between testosterone and lower urinary tract symptoms in men
In Ho Chang1, Seung Young Oh, Sae Chul Kim
1Department of Urology, Chung-Ang University, College of Medicine, Seoul, Korea.
The Journal of Urology
|May 19, 2009
Summary
Lower testosterone levels are linked to more severe lower urinary tract symptoms in men. This suggests testosterone deficiency may play a role in the development of these symptoms and metabolic syndrome.
Area of Science:
- Andrology
- Urology
- Endocrinology
Background:
- Lower urinary tract symptoms (LUTS) are common in aging men.
- The relationship between testosterone levels and LUTS severity requires further investigation.
Purpose of the Study:
- To investigate the association between serum testosterone levels and the severity of lower urinary tract symptoms (LUTS) in men.
Main Methods:
- Serum levels of total testosterone, sex hormone-binding globulin, and calculated free and bioavailable testosterone were measured in 278 men.
- Prostate volume and LUTS severity (using International Prostate Symptom Score) were assessed.
- Adjustments were made for age, prostate volume, C-reactive protein, and insulin resistance.
Main Results:
- Calculated free testosterone and bioavailable testosterone showed a negative correlation with overall LUTS and voiding symptoms.
- Lower testosterone levels were significantly associated with the presence of severe LUTS.
- High-sensitivity C-reactive protein and insulin resistance were negatively correlated with total and free/bioavailable testosterone, but not directly with LUTS severity.
Conclusions:
- Endogenous testosterone plays a favorable role in lower urinary tract function.
- Testosterone deficiency may be a contributing factor to LUTS and metabolic syndrome in men.
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