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A Computer-Based Platform for Aiding Clinicians in Eating Disorder Analysis and Diagnosis
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Bulimia nervosa.

Phillipa J Hay1, Josue Bacaltchuk

  • 1School of Medicine, Campbelltown Campus, Western Sydney University, Sydney, Australia.

BMJ Clinical Evidence
|May 20, 2009
PubMed
Summary
This summary is machine-generated.

This systematic review evaluates treatments for bulimia nervosa, finding cognitive behavioral therapy and psychotherapy effective. It also examines discontinuing medication in remission for bulimia nervosa patients.

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Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Eating Disorders

Background:

  • Bulimia nervosa affects up to 1% of young women, characterized by binge-eating and compensatory behaviors.
  • Normal weight in affected individuals can complicate diagnosis.
  • Recovery rates vary, with 50% fully recovering, 33% partially, and 10-20% retaining symptoms after a decade.

Purpose of the Study:

  • To systematically review the effects of treatments for adult bulimia nervosa.
  • To assess the impact of discontinuing treatment in individuals with bulimia nervosa in remission.

Main Methods:

  • A systematic review of 26 studies, including systematic reviews, RCTs, and observational studies.
  • Searches conducted across major databases (Medline, Embase, Cochrane Library) up to June 2007.
  • Inclusion of harms alerts from regulatory agencies (FDA, MHRA).

Main Results:

  • Evidence quality was evaluated using the GRADE system.
  • A range of interventions were assessed for effectiveness and safety.

Conclusions:

  • Cognitive behavioral therapy (CBT), alone or with exposure response prevention, is effective.
  • Interpersonal psychotherapy and dialectical behavioral therapy show promise.
  • Pharmacological options including SSRIs, TCAs, mirtazapine, and venlafaxine were reviewed, alongside self-help and guided self-help CBT.