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Updated: Jun 23, 2026

Measuring Neural Mechanisms Underlying Sleep-Dependent Memory Consolidation During Naps in Early Childhood
Published on: October 2, 2019
Sleep disorders in children
Paul Montgomery1, Danielle Dunne
1University of Oxford, Oxford, UK.
Insights
This review examines treatments for childhood sleep disorders, including dyssomnias and parasomnias. It evaluates interventions like behavioral therapy, melatonin, and sleep hygiene for effectiveness and safety.
Area of Science:
- Pediatric Sleep Medicine
- Clinical Evidence Synthesis
Background:
- Sleep disorders affect 20-30% of young children, encompassing issues like excessive daytime sleepiness, difficulty sleeping (dyssomnias), and sleep disturbances (parasomnias) such as sleepwalking.
- Children with physical or learning disabilities face a higher risk of developing sleep disorders.
Purpose of the Study:
- To systematically review the effects of treatments for dyssomnias in children.
- To systematically review the effects of treatments for parasomnias in children.
Main Methods:
- A systematic review was conducted, searching major databases up to September 2006.
- Included studies were 14 systematic reviews, randomized controlled trials (RCTs), or observational studies.
- GRADE evaluation was used to assess the quality of evidence for interventions.
Main Results:
- The review identified and evaluated various interventions for childhood sleep disorders.
- Evidence quality for different treatments was assessed using the GRADE system.
Conclusions:
- Information on the effectiveness and safety of interventions including antihistamines, behavioral therapy, melatonin, and sleep hygiene is presented.
- Specific interventions evaluated include scheduled waking for parasomnias and safety measures.
Introduction:
Sleep disorders may affect 20-30% of young children, and include excessive daytime sleepiness, problems getting to sleep (dysomnias), or undesirable phenomena during sleep (parasomnias), such as sleep terrors, and sleepwalking. Children with physical or learning disabilities are at increased risk of sleep disorders.
Methods And Outcomes:
We conducted a systematic review and aimed to answer the following clinical questions: What are the effects of treatments for dysomnias in children? What are the effects of treatments for parasomnias in children? We searched: Medline, Embase, The Cochrane Library and other important databases up to September 2006 (Clinical Evidence reviews are updated periodically, please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA).
Results:
We found 14 systematic reviews, RCTs, or observational studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.
Conclusions:
In this systematic review we present information relating to the effectiveness and safety of the following interventions: antihistamines, behavioural therapy plus benzodiazepines, or plus chloral and derivates, exercise, extinction and graduated extinction, light therapy, melatonin, safety/protective interventions for parasomnias, scheduled waking (for parasomnias), sleep hygiene, and sleep restriction.
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