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Related Concept Videos

Chronic Pancreatitis I: Introduction01:25

Chronic Pancreatitis I: Introduction

Chronic pancreatitis is a long-standing, relapsing inflammation of the pancreas, characterized by irreversible damage to the gland. It results in progressive destruction of the pancreatic parenchyma, fibrosis, and eventual loss of both exocrine and endocrine function. The disease may evolve gradually after multiple episodes of acute pancreatitis or develop independently.EtiologyChronic pancreatitis can arise from a variety of causes:Alcohol use is the leading cause, accounting for 70–80% of...
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Chronic Pancreatitis II: Pathophysiology01:21

Chronic Pancreatitis II: Pathophysiology

Chronic pancreatitis is a progressive and irreversible inflammation of the pancreas, most often caused by long-term alcohol abuse, but it can also be related to ductal obstruction, smoking, or genetic factors.Chronic pancreatitis occurs when the pancreas is repeatedly exposed to harmful agents like alcohol, smoking, ductal obstruction, or genetic predisposition. These factors lead to the release of toxic metabolites and inflammatory cytokines, sustaining chronic inflammation in the pancreatic...
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
Chronic Inflammation: Introduction01:12

Chronic Inflammation: Introduction

Chronic inflammation is a prolonged, dysregulated immune response that persists for weeks to years when the inciting stimulus is difficult to eradicate or when self‑antigens drive ongoing reactivity. Morphologically, it is defined by mononuclear cell infiltration, progressive tissue destruction, and concurrent attempts at healing via angiogenesis and fibrosis. Compared with acute inflammation, edema is less prominent while cellular infiltration predominates; triggers include persistent...
Chronic Pharyngitis01:23

Chronic Pharyngitis

Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...

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Related Experiment Video

Updated: Jun 23, 2026

Assessment of Perigenital Sensitivity and Prostatic Mast Cell Activation in a Mouse Model of Neonatal Maternal Separation
09:49

Assessment of Perigenital Sensitivity and Prostatic Mast Cell Activation in a Mouse Model of Neonatal Maternal Separation

Published on: August 13, 2015

Chronic prostatitis.

Bradley A Erickson1, Anthony J Schaeffer, Brian Van Le

  • 1Department of Urology, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA.

BMJ Clinical Evidence
|May 20, 2009
PubMed
Summary
This summary is machine-generated.

This systematic review evaluates treatments for chronic prostatitis, including bacterial and abacterial forms (chronic pelvic pain syndrome). It found 30 studies on interventions like alpha-blockers and anti-inflammatory drugs, assessing their effectiveness and safety.

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Measurement of Tactile Allodynia in a Murine Model of Bacterial Prostatitis
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Measurement of Tactile Allodynia in a Murine Model of Bacterial Prostatitis

Published on: January 16, 2013

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Last Updated: Jun 23, 2026

Assessment of Perigenital Sensitivity and Prostatic Mast Cell Activation in a Mouse Model of Neonatal Maternal Separation
09:49

Assessment of Perigenital Sensitivity and Prostatic Mast Cell Activation in a Mouse Model of Neonatal Maternal Separation

Published on: August 13, 2015

Measurement of Tactile Allodynia in a Murine Model of Bacterial Prostatitis
06:46

Measurement of Tactile Allodynia in a Murine Model of Bacterial Prostatitis

Published on: January 16, 2013

Area of Science:

  • Urology
  • Evidence-Based Medicine
  • Pharmacology

Background:

  • Chronic prostatitis presents with pain and urinary symptoms, often without bacterial infection (chronic abacterial prostatitis/chronic pelvic pain syndrome).
  • The etiology and natural history of chronic pelvic pain syndrome remain largely unknown.
  • Bacterial prostatitis can arise from urinary tract instrumentation.

Purpose of the Study:

  • To systematically review the effects of treatments for chronic bacterial prostatitis.
  • To systematically review the effects of treatments for chronic abacterial prostatitis/chronic pelvic pain syndrome.

Main Methods:

  • A systematic literature search was conducted across major databases (Medline, Embase, Cochrane Library) up to August 2007.
  • Included studies comprised systematic reviews, randomized controlled trials (RCTs), and observational studies.
  • GRADE methodology was employed to evaluate the quality of evidence for various interventions.

Main Results:

  • Thirty studies met the inclusion criteria for the review.
  • The review synthesized evidence on a wide range of interventions.
  • GRADE evaluation assessed the quality of evidence for each treatment.

Conclusions:

  • The review provides information on the effectiveness and safety of numerous interventions for chronic prostatitis.
  • Interventions evaluated include 5 alpha-reductase inhibitors, alpha-blockers, NSAIDs, and prostatic massage.
  • Other treatments assessed encompass quercetin, sitz baths, and transurethral therapies.