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Chronic Pancreatitis I: Introduction

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...

Chronic Pancreatitis II: Collaborative Care

Chronic Pancreatitis II: Collaborative Care

The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:

Acute Pancreatitis II: Clinical Manifestations and Management

Acute Pancreatitis II: Clinical Manifestations and Management

Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...

Pancreas

Pancreas

The pancreas, an essential organ in the human body, is a pinkish-gray elongated structure located posterior to the stomach. It extends laterally from the duodenum towards the spleen and is firmly bound to the posterior wall of the abdominal cavity. The organ's surface has a lumpy, lobular texture that gives it a unique appearance.
The broad head of the pancreas lies within the loop formed by the duodenum, while its slender body reaches towards the spleen. The tail of the pancreas is short...

Acute Pancreatitis I: Introduction

Acute Pancreatitis I: Introduction

Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:

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Related Experiment Video

Updated: Nov 9, 2025

Oncogene Expression Analysis with Alterations in pH in a Pancreatic Ductal Cell Line

Oncogene Expression Analysis with Alterations in pH in a Pancreatic Ductal Cell Line

Published on: April 11, 2025

Pancreatic cancer.

Adrian O'Sullivan¹, Hemant M Kocher

¹Barts and The London HPB Centre, Royal London Hospital, London, UK.

BMJ Clinical Evidence

|May 20, 2009

Summary

This summary is machine-generated.

This systematic review evaluates surgical and adjuvant treatments for pancreatic cancer, finding various chemotherapies and surgical techniques effective. Further research is needed to optimize pancreatic cancer patient outcomes.

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Last Updated: Nov 9, 2025

Oncogene Expression Analysis with Alterations in pH in a Pancreatic Ductal Cell Line

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Laparoscopic Pancreatoduodenectomy for Pancreatic Cancer Using In-Situ No-Touch Isolation Technique

Laparoscopic Pancreatoduodenectomy for Pancreatic Cancer Using In-Situ No-Touch Isolation Technique

Published on: February 2, 2022

Area of Science:

Oncology
Surgical Gastroenterology
Evidence-Based Medicine

Background:

Pancreatic cancer has a poor prognosis, with a 5-year survival rate of only 5% in higher-income countries.
Risk factors include smoking, alcohol, diet, diabetes mellitus, and pancreatitis.
Early-stage diagnosis offers limited survival benefits.

Purpose of the Study:

To systematically review the effects of surgical treatments for resectable pancreatic cancer.
To evaluate the impact of adjuvant treatments in patients with completely resected pancreatic cancer.

Main Methods:

Conducted a systematic literature review up to November 2006.
Searched major databases including Medline, Embase, and The Cochrane Library.
Included studies such as systematic reviews, RCTs, and observational studies, with GRADE evaluation of evidence quality.

Main Results:

Identified 31 relevant systematic reviews, RCTs, and observational studies.
Evaluated the effectiveness and safety of numerous interventions.
Included data on chemoradiotherapy, various chemotherapy regimens (fluorouracil-based, gemcitabine-based), and surgical procedures.

Conclusions:

Presents information on the effectiveness and safety of diverse interventions for pancreatic cancer.
Covers surgical options like pancreaticoduodenectomy (Whipple's procedure) and lymphadenectomy.
Details adjuvant therapies including chemoradiotherapy and chemotherapy regimens.